About AOD-9604 - Fat Cell Lipolysis Peptide

AOD-9604 is a modified fragment of human growth hormone designed to trigger fat breakdown (lipolysis) and prevent new fat storage without impacting blood sugar or IGF-1 levels. It Is relatively mild and mainly targets stubborn pockets of fat.

WHAT THE RESEARCH SHOWS

* Mechanism of Action: In preclinical studies, it was shown to stimulate lipolysis (breaking down stored fat) and inhibit lipogenesis (preventing new fat storage) by triggering beta-3 adrenergic receptors on fat cells. Crucially, it does this without affecting blood glucose, insulin sensitivity, or cell proliferation.
* Human Clinical Trials (The Phase II Results): Unlike many research peptides, AOD-9604 actually went through human trials conducted by an Australian biotech company (Metabolic Pharmaceuticals) in the early 2000s on roughly 900 patients. * Safety: It passed safety profiles with flying colors no negative impact on blood sugar, cholesterol, or organ markers.
* Joint & Cartilage Repair: More recent animal studies showed a secondary benefit: it can promote cartilage regeneration and reduce pain in osteoarthritis models, especially when paired with hyaluronic acid.

STUDIES

Heffernan et al., 2001 (International Journal of Obesity). In obese mice, AOD-9604 reduced weight gain, increased fat oxidation and stimulated lipolysis. Unlike full growth hormone, it did not cause high blood sugar or reduce insulin secretion. Nature PDF - LINK

Lyophilised powder