About CJC-1295 (NO dac) - Repair / Composition Peptide

CJC-1295 is a growth hormone-releasing hormone (GHRH) analogue that signals your pituitary gland to release higher, natural pulses of growth hormone to improve lean muscle recovery, fat loss, and deep sleep. It's rarely run solo because it works best in the 2-in-1 CJC-1295 + Ipamorelin combo pairing them triggers two different pathways for a much stronger, synergistic GH release without spiking prolactin or cortisol.

WHAT THE RESEARCH SHOWS

* Mimics Natural Pulsatile GH Release: Because it does not contain the "DAC" (Drug Affinity Complex), it doesn't cause a continuous, unnatural "GH bleed." Instead, it triggers a clean, physiological spike of growth hormone that aligns with your body’s natural circadian pulses, avoiding pituitary desensitization.
* Elevates IGF-1 Levels: Clinical studies show that regular stimulation of GHRH receptors translates to sustained baseline increases in circulating IGF-1 (Insulin-like Growth Factor 1). This drives cellular repair, deeper slow-wave sleep, and improved nitrogen retention for muscle preservation.
* Minimal Side Effects on Cortisol & Prolactin: Unlike older, non-selective growth hormone secretagogues, CJC-1295 acts selectively on pituitary GHRH receptors without spiking cortisol, prolactin, or blood glucose. The Bottom Line: While CJC-1295 (no DAC) works well on its own, research shows it only opens the pituitary "floodgates." To get the absolute best pulse for muscle growth, fat loss, and recovery, the CJC-1295 + Ipamorelin combo is the gold standard 2-in-1 blend. CJC-1295 triggers the release while Ipamorelin amplifies the pulse size, creating a massive synergistic effect far beyond running either peptide solo.

STUDIES

Teichman et al., J Clin Endocrinol Metab 2006, 91:799–805 One injection raised growth hormone 2–10× for 6+ days and IGF-1 1.5–3× for 9–11 days. Half-life was about 6–8 days. With repeat doses, IGF-1 stayed raised for up to 28 days. No serious side effects were reported. Pubmed
CJC-1295 Wikipedia

Lyophilised powder